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KMID : 0367419940370030383
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Journal of Korean Pediatric Society
1994 Volume.37 No. 3 p.383 ~ p.389
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Clinical Analysis of Serum and Urine N-Acetyl-B-D-Glucosaminidase(NAG) in Renal Disease
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정요한
임인석/김철하/유병훈/심태섭
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Abstract
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Recently, NAG activity has gained increasing importance as and aid in the diagnosis of renoparenchymal diseases. Elevation of urine NAG activity has been found to be an indicator of renoparenchymnal diseases. To evaluate the diagnostic value of
the
NAG
activity test in the renal disease, we carried out clinical study on 31 cases of renal disease patients who had been admitted to the Department of Pediatrics, Chung-Ang University Hospital between March 1992 and February 1993.
We analyese by two data: (1) Stastical Package for the Social Science. ⑵ Students'T test.
@ES The results were as follows
@EN 1) The urine NAG activity significantly increased (p<0.05) to 69.9±5165.69U/hr/mg Creatinine (U/hr/mg Cr) in the renal disease group compared to 3.6±1.91U/hr/mg Cr in the control group.
2) The serum NAG activity was 11.69±5.18U/L in the renal disease group and 10.58±4.04U/L in the control group. There was no significant difference in the serum NAG sctivity between two groups.
3) In the renal disease group, the serum NAG activity was 10.78±3.32U/L in male 12.53±6.47U/L in female. There was no significant difference between both sexes. In the renal disease, the urine NAG activity was 33.62±30.67U/hr/mg Cr in male
and
114.05±241.62U/hr/mg Cr female. There was no significant difference between both sexes (p<0.05).
4) In the renal disease group, the urine NAG activity increased 314.73±420.39U/hr/mg Cr in the 2 years old group but there was no significant difference of urine NAG activity compared to above 2 years old group .
5) The urine NAG activities were 93.1±0193.04U/hr/mg Cr in the poteinuria subgroup and 13.3±47.62U/hr/mg Cr in the nonproteinuria subgroup and 3.66±1.91U/hr/mg Cr in the control group. There was no significant difference between the
proteinuria
subgroup and the nonproteinuria subgroup. but there was significant difference between nonproteinuria subgroup and control grouop(p<0.005).
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KEYWORD
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